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100 Most Innovative Machine Learning Startups & Companies (Illinois)

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This article showcases our top picks for the best Illinois based Machine Learning companies. These startups and companies are taking a variety of approaches to innovating the Machine Learning industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top Illinois Machine Learning Startups

Data sourced from Crunchbase and SemRush.

4Degrees

4Degrees

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AI-enabled relationship management platform, built for relationship driven industries.

Uptake Technologies

Uptake Technologies

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Uptake Technologies designs and develops enterprise software.

Uptake Technologies

Arturo

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Arturo is a deep learning spin-out from a Fortune 500 company focused on delivering highly accurate measurement and predictive data.

Uptake Technologies

Venzee Technologies

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Venzee is the artificial intelligence platform for consumer brands to send product data to all of their retailers with infinite scale.

Uptake Technologies

Prenosis

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Transforming clinical diagnosis with predictive intelligence.

Uptake Technologies

Convr

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Convr empowers commercial insurance carriers with frictionless underwriting to enable optimal efficiency.

Uptake Technologies

Jiobit

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Jiobit is an electronics company that manufactures the world’s smallest and longest self learning location tracking technology.

Uptake Technologies

ModelOp

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Pioneer of ModelOps software enabling enterprises to address the critical governance and scale challenges in operationalizing AI/ML models

Uptake Technologies

Tempus

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Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

Uptake Technologies

EarthSense

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EarthSense is an agricultural intelligence for a sustainable planet.

Uptake Technologies

Samya.AI

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Samya.AI operates as a revenue growth AI company that brings the power of deep learning.

Uptake Technologies

FourKites

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FourKites is a supply chain visibility platform designed for transportation into yards, warehouses, and stores.

86 Repairs

Blinkfire Analytics

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Blinkfire Analytics uses proprietary, patented AI and computer vision to optimize the sponsorship marketplace across social media, digital, and OTT for teams, leagues, athletes, creators, and brands. 

Uptake Technologies

Koios Medical

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Koios Medical is a leading healthcare into the era of machines & supporting physicians in delivering exceptional care.

Uptake Technologies

Tackle AI

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TackleAI is an algorithms and neural network that automatically discover data on any type of document or image.

Uptake Technologies

Click Deal Buy!

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Click Deal Buy! specializes in the fields of artificial intelligence, machine learning, big data, and analytics.

Uptake Technologies

Murmur

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SaaS AI analytics platform to target audiences on street and measure outdoor ad performance in real-time.

Uptake Technologies

Metopio

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Metopio is a data, analytics, and visualization platform.

Uptake Technologies

Heretik

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Heretik is a Chicago-based software company using machine learning to make the contract review process easier and smarter.

Uptake Technologies

Telegraph System

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Telegraph System is a SaaS transportation technology startup that digitize a critical segment of the supply chain.

Uptake Technologies

Entigenlogic

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Entigenlogic is an artificial intelligence software company.

Uptake Technologies

Inference Analytics, Inc.

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Deep tech company using leading edge AI based work on text and images to assist diagnosis in dentistry and medicine.

Uptake Technologies

Speeko

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Automated voice analytics and digital communication coaching

Uptake Technologies

simMachines

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simMachines provides similarity-oriented solutions for advanced analytics.

Uptake Technologies

Jovian Technologies

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AI SaaS platform for Food & Beverage Competitive Intelligence & Consumer data Analytics

Uptake Technologies

Inspirit IoT

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Inspirit IoT is a computer hardware that provides solutions in machine learning to cloud, server and edge devices.

Uptake Technologies

The Collaboratory

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A B2B SaaS company building AI-powered document discovery tools for biopharma companies

Uptake Technologies

Esquify

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Esquify is a software company that provides AI automation workforce management solutions for legal review.

Uptake Technologies

SetuServ

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SetuServ is a text analytics firm focused on building Voice of Customer solutions using Natural Language Processing and curation.

Uptake Technologies

UrbanStat

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UrbanStat helps P&C insurance carriers to improve their loss ratio by up to 7% with geostatistics and machine learning.

Uptake Technologies

NutriSense

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NutriSense personalizes nutrition by leveraging state of the art continuous glucose monitoring and machine learning technology.

Uptake Technologies

p3rceive

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Sales simulation and modeling engine.

Uptake Technologies

Vitrix Health

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We built an oral disease screening platform using AI and imaging to allow any medical professional to catch oral diseases earlier.

Uptake Technologies

Speciate AI

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Speciate AI provides an AI driven solution to help companies understand what the market feels about their products and identify ways to grow

Uptake Technologies

Acer Innovation

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Acer Innovation is a global analytics firm leveraging data science to help Fortune 500 firms.

Uptake Technologies

Data Products LLC

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Data Science Consulting

Uptake Technologies

AiRo Digital Labs

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AiRo Digital Labs is an emerging tech solutioning company specializing in transforming healthcare ecosystem

Uptake Technologies

SmarterCloud

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SmarterCloud is a cybersecurity platform that isolates and secures customer data.

Uptake Technologies

CareBand

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Wearable technology for seniors living with dementia

Uptake Technologies

Strong Analytics

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Strong Analytics is a provider of custom machine learning software and solutions.

Uptake Technologies

Kamion

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Kaimon is an intelligent truck management software that helps to dispatchers optimize drivers’ time on the road.

Uptake Technologies

Ameex Technologies

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Ameex Technologies is a Digital Transformation partner delivering AI enabled content and personalized commerce solutions.

Uptake Technologies

Zuci Systems

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Zuci is revolutionizing the way software platforms are engineered with the help of patented AI and deep learning models.

Uptake Technologies

Sleek Technologies

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Freight Management Saas and Data

Uptake Technologies

Cardiosense

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Cardiosense is building a physiological waveform AI platform to develop predictive biomarkers for the detection and treatment of disease.

Uptake Technologies

Sensefolio

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Artificial Intelligence ESG Data startup specialized in socially responsible investment #AI #ESG #SRI #AM #FinTech

Uptake Technologies

SAVVI

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SAVVI AI is a low-code, end-to-end Machine Learning tool, empowering teams to quickly and easily create products that learn.

Uptake Technologies

CLOUDQUANT, LLC

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CloudQuant a powerful and comprehensive data + tech+ research + distribution platform for investors and corporate clients

Uptake Technologies

Defend Edge

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DefendEdge’s SiON, an Employee Threat Management platform predicts, detects, and prevents human based identity access insider threats

Uptake Technologies

Powerupcloud Technologies

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Powerupcloud is a cloud technology company with product & services in cloud migrations, managed cloud and AI solutions.

Uptake Technologies

Socian Technologies

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Socian Technologies is building autonomous drone systems that serve as the ultimate accountability tool for safer community policing.

Uptake Technologies

LAGOM

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At LAGOM, we are working for making the world a better place with the power of AI and high technologies.

Uptake Technologies

GENINVO

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GenInvo provides software development covering data anonymization, document management, AI & machine learning for the life science industry.

Uptake Technologies

Altris.AI

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SaaS, Mobile App, ophthalmology deep learning platform for automatic, quantitative analysis and detection retinal diseases.

Uptake Technologies

Nousot

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Nousot develops machine learning products to deliver predictive analytics as a service in the field of data science.

Uptake Technologies

Bounte

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BOUNTE is an intelligent lost and found app and web platform that modernizes and streamlines the lost and found operations for hotels

Uptake Technologies

Shortest Track Company

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Shortest Track manages and accelerates the intelligence supply chain for business executives.

Uptake Technologies

StreamAI

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StreamAI builds innovative, solutions-focused AI for the Enterprise. Tools, not toys.

Uptake Technologies

Pikato, Inc

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Mobile Marketing Automation, evolved

Uptake Technologies

Aerospec Technologies

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We develop fully autonomous robotic technologies and cloud based data analytics for industrial inspections.

Uptake Technologies

DemandWorks Media

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DemandWorks’ unique lead generation programs enable you to deliver your content, to the right buyer, at the right time, on any device.

Uptake Technologies

7QUBES

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SaaS, FinTech, Distributed Ledger Technology, Blockchain, AI, ERP

Uptake Technologies

Beyond Expression

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Smart solutions for communication data extraction and efficiency improvement

Uptake Technologies

Salient Global

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Salient Global help those we serve flourish by delivering meaningful, data-driven human experiences.

Uptake Technologies

Aiolux

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Automated Investment Research using Quant Finance, Statistics& AI / ML. (Think Bloomberg meets AWS)

Uptake Technologies

Potentia Analytics

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SAAS, Healthcare: Command Center, Patient Flow Optimization, Provider Scheduling | Policy and Decision Making: Predictive Analytics

Uptake Technologies

SpotMyPhotos

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SpotMyPhotos is a photo sharing platform that uses a variety of cloud-based, pattern recognition, and machine learning technologies.

Uptake Technologies

Aboriginal Armadillo

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Startup focused on Natural Language Generation and Image Processing.

Uptake Technologies

IPgallery

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Founded in 2000, IPgallery is a software development and integration company.

Uptake Technologies

Acies

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Acies helps organizations with digital transformation by utilizing a unified framework of technology, data, insights, design, and strategy.

Uptake Technologies

Temporal Games

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Game Development, AI Research and Deployment

Uptake Technologies

7 Senses Labs

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Story-based Adaptive Learning Solutions for Children

Uptake Technologies

Entrigna

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Entrigna offers RTES, a real time expert system platform that translates complex data and predictive analytics into actionable insights.

Uptake Technologies

Tercero Technologies

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Advanced Edge Artificial Intelligence

Uptake Technologies

DeCypher DataLabs

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DeCypher DataLabs is a scientific research and product development company in the field of Artificial Intelligence.

Uptake Technologies

Language.ai

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NLP / ML consulting and related SaaS linguistic annotation solutions.

Uptake Technologies

Enlistics

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Enlistics is a hiring startup that uses advanced statistics and machine learning to algorithmically match applicants & businesses.

Uptake Technologies

VectorScient

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VectorScient is a cloud-native, AI driven Marketing Analytics platform for e-commerce businesses.

Uptake Technologies

Metonymy Labs

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Metonymy Labs is developing the best platform for machine learning researchers to put their ideas into commercial action.

Uptake Technologies

Juvle

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Using artificial intelligence & machine learning, Juvle helps parents discover kids’ classes and events in every city and every town.

Uptake Technologies

MoonWorks

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MoonWorks uses NLP (Natural Language Processing) to foster more natural communication between humans and artificial intelligence.

Uptake Technologies

INTELLIC.AI

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Saas, Clinical Data, Clinical Prediction Models, Validation, Development, Intelligence, Predictive Analytics

Uptake Technologies

QuaXigma

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QuaXigma is an IT firm that offers cloud computing, SaaS, AI, machine learning, retail and product development solutions.

Uptake Technologies

Digintel

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Digintel is an AI and automated machine learning platform for predictive & prescriptive analytics.

Uptake Technologies

Vu360 Solutions

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Vu360 Solutions renders artificial intelligence, machine learning and IoT services for healthcare, food supply and agriculture industries.

Uptake Technologies

Netrolix, LLC

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AI, Machine Learning, Software Defined Networking and Orchestration

Uptake Technologies

botsensei

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A hands-on approach to learning self driving car technologies

Uptake Technologies

SKORBOARD

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SKORBOARD is to develop a fully integrated enterprise for data analysis, data mining, business reporting and predictive analytics

Uptake Technologies

Degree Six

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AI and Analytics Consulting

Uptake Technologies

Oscillas Technologies

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Application development and machine learning

Uptake Technologies

Authentic Learning Labs

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Authentic Learning Labs is an e-learning company. It is specialized in learning analytics, business intelligence, and more.

Uptake Technologies

KSSA, Inc.

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Machine learning technology to make business grow

Uptake Technologies

Optistics

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Intelligent Shipping Analytics Platform

Uptake Technologies

Whiz IT

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Whiz IT offers IT consulting, software development, CRM, ERP, cloud computing, machine learning, and software development services.

Uptake Technologies

Java-Dive Technologies

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Java-Dive Technologies develops software for robotic process automation and machine learning solutions.

Uptake Technologies

LR Data Science

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At LR Data Science, we run quick audits on organizations wanting to get their share of the booming Online Market.

Uptake Technologies

Hoyt Niva Consulting Inc. (hoytNIVA)

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hoytNIVA is an IT consulting firm specializing in cyber-security, data analytics, machine learning and human capital.

Uptake Technologies

Wellisch Software Technologies

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Wellisch Software Technologies offers database design/development, software engineering, and machine learning/artificial intelligence.

Uptake Technologies

Bite Size Legal

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We are on a mission to empower 28.1 million renters with machine learning, mobile technology & data science.

Uptake Technologies

AFIRI

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AFIRI provides machine learning-based underwriting as a service for emerging economies.

Written by Mark Smith

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