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101 Most Innovative Machine Learning Startups & Companies (Massachusetts)

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This article showcases our top picks for the best Massachusetts based Machine Learning companies. These startups and companies are taking a variety of approaches to innovating the Machine Learning industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top Massachusetts Machine Learning Startups

Data sourced from Crunchbase and SemRush.

LinkSquares

LinkSquares

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LinkSquares is a provider of AI-powered contract management tools for in-house legal teams.

Activ Surgical

Activ Surgical

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Activ Surgical is a digital surgery company focused on improving surgical efficiency, accuracy, patient outcomes, and accessibility.

Activ Surgical

Relativity6

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Relativity6 is The Industry Classification API.

Activ Surgical

Indico Data

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Indico Data transforms unstructured data into actionable insights.

Activ Surgical

nference

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nference.inc, provides an AI based software platform that synthesizes siloed biomedical knowledge for insights and makes it computable.

Activ Surgical

Cogito

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Cogito enhances the emotional intelligence of phone professionals by applying behavioral science through artificial intelligence.

Activ Surgical

OnCorps

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OnCorps is a provider of decision and behavioral science into machine learning nudges to help people make better decisions.

Activ Surgical

Crayon

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Crayon is an intelligence platform that helps businesses track, analyze, and act based on market movements.

Activ Surgical

Lightmatter

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Lightmatter uses light to create photonic compute chips specialized for AI.

Activ Surgical

Quantiphi

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Quantiphi is a category defining data science and machine learning software and services company.

Activ Surgical

Alyce

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Alyce is an AI-powered Personal Experience Platform empowers Marketers and Sellers to build bonds with their prospects & customers at scale.

Activ Surgical

Bigtincan

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Bigtincan Sell Smarter, Learn Faster, and Win More with the industry’s leading AI-powered Sales Enablement Automation Platform.

Activ Surgical

VIA

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VIA helps energy companies realize the value of their data through Artificial Intelligence (AI) and Blockchain.

Activ Surgical

Buoy Health

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Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.

Activ Surgical

Tamr

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Tamr is an enterprise data unification company that is cost-effective, scalable, and accessible to any enterprise.

Activ Surgical

Wise Systems

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Wise Systems’ autonomous dispatch and routing software uses AI to improve fleet efficiency and customer service for last-mile operations.

Activ Surgical

StormForge

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StormForge brings together data scientists and software engineers to enable businesses to drive breakthrough IT and operations efficiency.

Activ Surgical

Evolv Technology

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Evolv Technology, an AI-enabled touchless security screening system that uses digital sensors and artificial intelligence to detect threats.

Activ Surgical

Gradient AI

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Gradient AI is a provider of Artificial Intelligence and Machine Learning based solutions designed specifically insurance industry.

Activ Surgical

CloudZero

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CloudZero is a SaaS platform offering real-time cost anomaly and waste detection to optimize cloud costs and prevent accidental overspend.

Activ Surgical

American Robotics

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American Robotics is a Robot-as-a-Service company that develops FAA-approved pilotless, AI-powered drones for industrial purposes.

Activ Surgical

Finch Therapeutics

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Finch Therapeutics is a microbiome development company that serve patients with serious unmet medical needs.

Activ Surgical

Yobe

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Yobe is a software company that develops artificial intelligence-powered for the enhanced processing of communications signals.

Activ Surgical

Affectiva

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Affectiva is a developer of an emotion-recognition software designed to analyze subtle facial and vocal expressions.

Activ Surgical

Neural Magic

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Neural Magic is stealth stage machine learning company, based in Somerville MA.

Activ Surgical

Kensho

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Kensho combines natural language search, graphical user interfaces, and secure cloud computing to create a new class of analytics tools.

Activ Surgical

ISEE

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We’re an autonomous driving technology company building advanced AI to modernize the global supply chain.

Activ Surgical

Elemental Machines

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Smart lab platform delivers powerful, data-driven insights that improve R&D, laboratory operations, and manufacturing outcomes.

Activ Surgical

DataRobot

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DataRobot brings AI technology and ROI enablement services to global enterprises.

Activ Surgical

Zoovu

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Zoovu is the next generation digital commerce search platform.

Activ Surgical

Interactions

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Interactions develops award-winning intelligent virtual assistant solutions used by Fortune 500 companies worldwide.

Activ Surgical

Mainstay

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Mainstay is a developer of a chatbot platform that increases student engagement, enrollment, and success.

Activ Surgical

Neurala

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Neurala provides an AI platform that empowers companies to automate visual inspections.

Activ Surgical

RapidMiner

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RapidMiner builds a software platform for data science teams that unites data prep, machine learning, and predictive model deployment.

Activ Surgical

OfferFit

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OfferFit selects the best message, incentive, timing, and channel for every customer.

Activ Surgical

Slang

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Slang offers a variety of online specialized English courses for career development using a proprietary ML-driven engine,

Activ Surgical

Attivio

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Attivio provides natural language processing, machine learning, text analytics, and AI-powered search capabilities at scale.

Activ Surgical

Posh

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Posh is a conversational AI and NLP technology development company that enables developers to deliver a new way to interact with users.

Activ Surgical

Infinite Analytics

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AI platform that democratizes data based consumer insights for companies and individuals to analyze consumer behavior and action on it.

Activ Surgical

Connected2Fiber

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Connected2Fiber is an industry platform for connectivity, cloud, and communications that drives growth through location intelligence.

Activ Surgical

GenesisAI

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GenesisAI is an Artificial Intelligence marketplace that allows companies to buy or sell AI products and services

Activ Surgical

Elucidata

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Elucidata delivers ML-ready biomedical molecular data that is curated to accelerate drug discovery.

Activ Surgical

Vocalis Health

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Vocalis Health is to develop AI platform to enable healthcare.

Activ Surgical

FreightFlows

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FreightFlows is a maritime company that offers predictive analytics for global trade.

Activ Surgical

Cortex

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Cortex is a SaaS AI that enables marketing executives at leading brands to uncover what drives the performance of their visuals.

Activ Surgical

Beacon Biosignals

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Beacon’s goal is to improve human health by applying artificial intelligence to brain activity.

Activ Surgical

Reverie Labs

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Reverie Labs is a machine learning-driven pharma company.

Activ Surgical

Luminoso

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Luminoso is a new way for computers to understand language and turn text into actionable business intelligence.

Activ Surgical

Empatica

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Empatica is an affective computing company focused on human data analytics.

Activ Surgical

Kebotix

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Kebotix is a high-tech materials discovery and production company that reinvent the discovery of new materials using AI.

Activ Surgical

Swoop

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Swoop is a provider of artificial intelligence and machine learning solutions to find, engage, and convert the ideal patient population.

Activ Surgical

Celect

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Celect is a cloud-based, predictive analytics SaaS platform that helps retailers optimize their overall inventory portfolios.

Activ Surgical

ContextLabs

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ContextLabs provides enterprise platform solutions that deliver trust and transparency for the digital and physical worlds.

Activ Surgical

XYZ Robotics

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XYZ Robotics develops AI-enabled robotic perception and manipulation technology for logistics and manufacturing automation.

Activ Surgical

Jibo

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Jibo is a design-driven company that creates unforgettable experiences through advanced robotics technology.

Activ Surgical

Perceptive Automata

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Perceptive Automata enables those vehicles to understand what people might do next so they can navigate safely and smoothly around humans.

Activ Surgical

Inkbit

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Inkbit creats a next-generation additive manufacturing platform that combines 3D printing with machine vision.

Activ Surgical

Gesund

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Highway to clinical-grade AI

Activ Surgical

MarketMuse

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MarketMuse accelerates content research and builds AI-driven content strategies.

Activ Surgical

Common Sense Machines

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Common Sense Machines is building artificial intelligence that learns to translate the world into a 3D simulation.

Activ Surgical

Smartvid io

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Our AI-powered Safety Suite helps companies identify their highest risk projects and act to prevent incidents from occurring.

Activ Surgical

Root AI

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Root AI is a research company aiming to create intelligent robots that will help growers build the farms of the future.

Activ Surgical

GreatHorn

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GreatHorn provides protection for cloud email systems, via advanced threat detection, automated defense, and integrated incident response.

Activ Surgical

Nabla Bio

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Nabla Bio is an autoverse platform of proprietary biologically informed machine learning that co-develops antibody drugs.

Activ Surgical

ConnectM Technology Solutions

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ConnectM brings remote efficiency, insight, and control to the operations of mechanical equipment using a powerful sensor and AI platform.

Activ Surgical

Modulate

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Modulate creates customizable voice skins for games & using machine learning to make voice completely customizable.

Activ Surgical

Talla

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Talla Brings AI-Powered Automation to Service and Support Teams

Activ Surgical

MIT-IBM Watson AI Lab

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MIT-IBM Watson AI Lab focuses on fundamental artificial intelligence research.

Activ Surgical

Dexai Robotics

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Dexai automates activities in commercial kitchens and the food industry more broadly.

Activ Surgical

Gamalon

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Gamalon is a developer of an AI-based machine intelligence technology designed to write and rewrite own Bayesian programs.

Activ Surgical

Ennoventure

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Ennoventure is a provider of smart and intelligent packaging systems for pharmaceutical.

Activ Surgical

Electra Vehicles, Inc.

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Electra is a tech start-up that brings the electric vehicle, fleet, and robotics markets to the next level with innovative AI/ML solutions.

Activ Surgical

Fritz AI

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Fritz AI is a machine learning platform for iOS and Android developers.

Activ Surgical

AdeptID

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AdeptID is the developer of machine-learning-powered talent matching software to support hidden talent in the workforce.

Activ Surgical

Gaiascope

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Gaiascope helps energy companies and investors transition to the future in the most economic way possible.

Activ Surgical

iSchoolConnect

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Artificial Intelligence, international student admission, international universities and colleges.

Activ Surgical

CircuitHub

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Deep learning and robotics to automate circuit board manufacturing.

Activ Surgical

Hyperplane Venture Capital

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Hyperplane Venture Capital is a seed stage investment firm focused on exceptional founders building machine intelligence and data companies.

Activ Surgical

FiVerity

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Intelligent Solutions for Cyber Fraud Detection in Financial Institutions

Activ Surgical

Findability Sciences

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Applies the power of big data, cognitive computing, and artificial intelligence (AI) in the award winning Findability Platform®.

Activ Surgical

MaxQ-AI

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MaxQ-AI delivers artificial intelligence based decision support to improve clinical outcomes.

Activ Surgical

RAGE Frameworks

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RAGE Frameworks is a knowledge-based automation technology and services.

Activ Surgical

AdaViv

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AdaViv is a hardware-enabled, predictive agriculture company.

Activ Surgical

Consensus

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Consensus is an ad-free, specialized search platform that delivers everyday people better scientific information using AI.

Activ Surgical

Rulex

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The ultimate platform for empowering your business with data-driven decisions.

Activ Surgical

Frase

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Frase is provides Artificial intelligence based market research assistant.

Activ Surgical

Bloomer Health Tech

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Bloomer Tech uses everyday fabrics and machine learning for personalized detection, monitoring, and treatment of chronic diseases.

Activ Surgical

Experfy

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Experfy is an operator of a consulting and upskilling platform used to address the scarcity of talent in the data science space.

Activ Surgical

Lazarus

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Lazarus uses patient health data to help physicians catch cancer early.

Activ Surgical

BlinkAI

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BlinkAI designs and develops artificial intelligence based application software to extract sensor information.

Activ Surgical

Botkeeper

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An intelligent bookkeeping automation platform powered by human-assisted AI, purpose built for accounting professionals.

Activ Surgical

Squark

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Squark is a no-code, automation-focused predictive analytics and machine learning SaaS verticalized for marketing analysts

Activ Surgical

Netra

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Netra is an image-recognition startup that offers visual intelligence and searches technology platforms using AI and Machine Learning.

Activ Surgical

Spiky.ai

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Spiky.ai uses video sentiment analytics to improve engagement.

Activ Surgical

GreenSight

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GreenSight is building the scaleable, enterprise platform for low altitude aerial intelligence.

Activ Surgical

Forge.AI

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Forge.AI develops AI systems intended to process unstructured information.

Activ Surgical

ReviveMed

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ReviveMed is a precision-medicine platform that leverages the data from small molecules or metabolites.

Activ Surgical

Totient

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Totient is an AI-driven biotechnology company that leverages tertiary lymphoid structures.

Activ Surgical

Synergies Intelligent Systems

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Synergies Intelligent Systems provides artificial intelligence services.

Activ Surgical

Vyasa Analytics

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Vyasa provides deep learning software & analytics for life sciences and healthcare organizations.

Activ Surgical

Basil Systems

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SaaS platform for healthcare companies

Written by Data Magazine

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